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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN2
All Species:
31.82
Human Site:
T527
Identified Species:
53.85
UniProt:
Q16513
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16513
NP_006247.1
984
112035
T527
L
V
R
R
A
I
P
T
V
N
H
S
G
T
F
Chimpanzee
Pan troglodytes
XP_001145367
984
112028
T527
L
V
R
R
A
I
P
T
V
N
H
S
G
T
F
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
P577
L
V
M
N
L
L
P
P
C
S
S
P
S
T
I
Dog
Lupus familis
XP_547295
1021
115999
T564
L
V
R
R
A
I
P
T
V
N
H
S
G
T
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWW9
983
111611
T526
L
V
R
R
A
I
P
T
V
N
H
S
G
T
F
Rat
Rattus norvegicus
O08874
985
112050
T528
L
V
R
R
A
I
P
T
V
N
H
S
G
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
V559
I
V
T
W
G
R
L
V
L
G
L
L
P
P
C
Chicken
Gallus gallus
XP_422357
1013
114806
T553
L
V
R
R
A
I
P
T
V
N
H
S
G
T
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_700704
970
110327
S520
L
V
R
R
A
I
P
S
P
N
N
S
F
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
S213
I
L
S
S
L
G
I
S
P
D
K
Q
Q
P
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
V286
C
S
T
C
K
L
N
V
H
K
R
C
Q
R
N
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
G378
P
I
Q
R
L
S
F
G
E
A
D
S
S
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
S677
S
L
G
L
T
D
L
S
I
E
H
S
Q
T
W
Red Bread Mold
Neurospora crassa
P87253
1142
127954
S629
I
A
Q
A
S
T
Y
S
G
S
T
A
Y
T
S
Conservation
Percent
Protein Identity:
100
99.6
46.1
92.8
N.A.
94.6
92.6
N.A.
53.9
87
N.A.
76.4
N.A.
28.3
N.A.
27.6
48.4
Protein Similarity:
100
99.9
63.2
94.7
N.A.
97.2
95.3
N.A.
68.2
91.9
N.A.
85
N.A.
42.3
N.A.
43.7
61.3
P-Site Identity:
100
100
26.6
100
N.A.
100
100
N.A.
6.6
100
N.A.
60
N.A.
0
N.A.
0
13.3
P-Site Similarity:
100
100
40
100
N.A.
100
100
N.A.
20
100
N.A.
80
N.A.
26.6
N.A.
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.1
27.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.6
45.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
50
0
0
0
0
8
0
8
0
0
0
% A
% Cys:
8
0
0
8
0
0
0
0
8
0
0
8
0
0
8
% C
% Asp:
0
0
0
0
0
8
0
0
0
8
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
8
8
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
43
% F
% Gly:
0
0
8
0
8
8
0
8
8
8
0
0
43
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
50
0
0
0
0
% H
% Ile:
22
8
0
0
0
50
8
0
8
0
0
0
0
0
8
% I
% Lys:
0
0
0
0
8
0
0
0
0
8
8
0
0
0
0
% K
% Leu:
58
15
0
8
22
15
15
0
8
0
8
8
0
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
8
0
0
50
8
0
0
0
8
% N
% Pro:
8
0
0
0
0
0
58
8
15
0
0
8
8
15
8
% P
% Gln:
0
0
15
0
0
0
0
0
0
0
0
8
22
0
0
% Q
% Arg:
0
0
50
58
0
8
0
0
0
0
8
0
0
8
8
% R
% Ser:
8
8
8
8
8
8
0
29
0
15
8
65
15
8
15
% S
% Thr:
0
0
15
0
8
8
0
43
0
0
8
0
0
65
0
% T
% Val:
0
65
0
0
0
0
0
15
43
0
0
0
0
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _